High-quality, real-time imaging of the cerebral cortex

Scientists and healthcare professionals have long been looking for technology for investigating the working brain without exerting too many constraints on the subjects, like with MRI, and with a spatial resolution higher than that of EEG. Non-invasive functional Near-infrared Spectroscopy (fNIRS) offers the ideal compromise between spatially highly accurate, but slow fMRI and the fast but spatially less accurate EEG in a subject-friendly, natural and controllable surroundings.

The state-of-the-art ETG-4100 uses the specific absorbance of near-infrared light by hemoglobin to precisely monitor cerebral blood flow. The system transmits near-infrared light through the skull to the cerebral cortex where the light absorbed by hemoglobin. With the aid of the modified Law of Lambert-Beer, changing concentrations in hemoglobin can be determined to pinpoint activated brain areas in the cerebral cortex.

Product pictures

  • Compact, mobile and user-friendly
    The user-friendly “plug-in and go” system is easily moved from room to room and quickly set up. It has an extremely user-friendly and efficient on-screen user interface and the wide-screen monitor provides a clear view of in-vivo- and analyzed data.
  • Simultaneous multi-channel measurements
    Hitachi developed a unique technology to identify multiple light sources simultaneously. This allows the ETG-4100 to monitor entire brain areas simultaneously, regardless how many light sources and measurement channels are being used and renders the system insensitive to ambient light. The system provides a wide range of fiber holders for simultaneously monitoring several independent brain areas with a capacity of 24 – 52 channels.
  • Versatile and innovative
    Hard- and software features make the system very flexible for a wide range of research and clinical applications. Neonate probes and infant fibers are available as well as customized fibers and fiber holders for specialized applications such as simultaneous NIRS/MRI or NIRS/EEG. The hard- and software have been optimized to meet the increasing demand for multimodal- or multi-distance measurements.
  • Measurement channels:
    Available in 24 and 48 channel configurations. 52 channels can be measured with an optional 3x11 probe.
  • Measurements:
    Changes in oxy-hemoglobin, deoxy-hemoglobin and total hemoglobin concentrations.
  • Light source:
    Laser diodes of two wavelengths (695nm and 830 nm) measure oxy- and deoxy-hemoglobin simultaneously. The shorter wavelength light source enables multi-faced measurements with very low levels of background noise.
  • Display format:
    Time-course graph display, 2D topographic images and mapped displays.
  • Sampling rate:
  • Interface:
    2 BNC ports, 4 digital in/ 4 digital out, 2 serial ports for external trigger and remote-control.
  • Network:
    1 LAN port
  • Data format:
    Hb raw data: text file format (csv) still images:BMP, animations: AVI, video: MPEG-4

The ETG-4100 has been engineered for safe and user-friendly use in clinical and research environments. Possible fields of application include cognitive neuroscience, psychology, psychiatry, neurology, rehabilitation, pediatrics and education.

  • Brain Mapping
  • Cognition
  • Psychiatric Disorders (depression, schizophrenia, dementia, ADHD, autism)
  • Pediatrics (development, language- and skill acquisition, social skills, learning difficulties)
  • Neurology (pre-surgical mapping of the hemispheric dominance for language, detectinge epileptic foci, stroke assessment and rehabilitation)
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